Constitutional Thinness: Unusual Human Phenotype of Low Bone Quality
نویسندگان
چکیده
منابع مشابه
Bone abnormalities in constitutional thinness
We would like to address some comments concerning the article titled ‘Thin healthy women have a similar low bone mass to women with anorexia nervosa’ by Fernández-Garcı́a et al. . While bone loss has often been reported in anorexia nervosa, the interesting part of this paper is the finding of a low total and lumbar bone mineral density in ‘thin healthy women’. In order to define a ‘thin healthy ...
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Clinical and biological aspects of restrictive anorexia nervosa (R-AN) are well documented. More than 10,000 articles since 1911 and more than 600 in 2013 have addressed R-AN psychiatric, somatic, and biological aspects. Genetic background, ineffectiveness of appetite regulating hormones on refeeding process, bone loss, and place of amenorrhea in the definition are widely discussed and reviewed...
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CONTEXT Anorexia nervosa (AN) presents an adaptive appetite regulating profile including high levels of ghrelin and 26RFa (orexigenic) and low levels of leptin and PYY (anorexigenic). However, this adaptive mechanism is not effective in promoting food intake. The NPY/proopiomelanocortin (POMC) system plays a crucial role in the regulation of feeding behavior as NPY is the most potent orexigenic...
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ژورنال
عنوان ژورنال: The Journal of Clinical Endocrinology & Metabolism
سال: 2008
ISSN: 0021-972X,1945-7197
DOI: 10.1210/jc.2007-1591